Breast cancer is cancer that develops from breast tissue. Risk factors for developing breast cancer include being female, obesity , lack of physical exercise, drinking alcohol , hormone replacement therapy during menopause , ionizing radiation , early age at first menstruation , having children late or not at all, older age, prior history of breast cancer, and family history. The balance of benefits versus harms of breast cancer screening is controversial. A Cochrane review stated that it is unclear if mammographic screening does more good or harm. Outcomes for breast cancer vary depending on the cancer type, the extent of disease , and the person's age. The first noticeable symptom of breast cancer is typically a lump that feels different from the rest of the breast tissue.
Breast Cancer Forum: HER2+ (Positive) Breast Cancer
The Breast Cancer Risk Assessment Tool allows health professionals to estimate a woman's risk of developing invasive breast cancer over the next 5 years and up to age 90 lifetime risk. The tool may underestimate risk in black women with previous biopsies and Hispanic women born outside the United States. Further studies are needed to refine and validate these models. This tool cannot accurately estimate breast cancer risk for: Women carrying a breast-cancer-producing mutation in BRCA1 or BRCA2 Women with a previous history of invasive or in situ breast cancer lobular carcinoma in situ or ductal carcinoma in situ Women in certain other subgroups see Other Risk Assessment Tools section. Although a woman's risk may be accurately estimated, these predictions do not allow one to say precisely which woman will develop breast cancer. In fact, some women who do not develop breast cancer have higher risk estimates than some women who do develop breast cancer.
HER2 Positive vs. HER2 Negative Breast Cancer
When NCI-supported researchers discovered that the HER2 gene is important for breast cancer growth, this led to the development of the drug trastuzumab and other targeted treatments that have improved survival for women with HER2-positive breast cancer. For years, doctors and researchers have noted that not all cancers are alike. But for other patients, their tumors grow rapidly and spread like wildfire. In the early s, after the discovery that a mutated gene called HER2 could stimulate excessive cell growth and division, many scientists wondered if certain genes might make cancers grow and spread rapidly. Researchers around the world began searching for genes that spur cancer growth.
Let friends in your social network know what you are reading about. A Utah mom had a "monster of a cancer. So she fought it with a unique treatment.